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Governed by the "3Rs" framework (Replacement, Reduction, and Refinement). Scientists seek to replace animals with alternative methods (like tissue cultures or computer models) where possible, reduce the number of animals used, and refine procedures to minimize pain.

However, the is slowly entering legal discourse. The Nonhuman Rights Project (NhRP) in the US is filing habeas corpus petitions on behalf of intelligent species—elephants, chimpanzees, whales—arguing for their "legal personhood." In 2022, an Argentine court recognized a female orangutan named Sandra as a "non-human person" with the right to freedom from captivity. This is a seismic shift from welfare towards rights.

Using non-animal alternatives (e.g., cell cultures, computer models) whenever possible.

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Animal rights philosophy, by contrast, rejects the notion that animals are commodities or resources for human use. Proponents argue that animals possess inherent value and have a moral right to life, liberty, and bodily integrity.

Minimizing the number of animals used in a given experiment.