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"Heat," Elias said. "I need to use a bulky, non-nucleophilic base, like 2,6-lutidine, to force elimination (E1) rather than substitution. I can re-form the double bond in the new, thermodynamically stable position."
Here are some sample practice problems to get you started: advanced organic chemistry practice problems
Number the carbons in both the starting material and the product. Identify exactly which bonds are broken and which new bonds are formed. "Heat," Elias said
Determining conrotatory vs. disrotatory ring closing/opening based on Δ (heat) or 3. Stereoselective Synthesis advanced organic chemistry practice problems
"Heat," Elias said. "I need to use a bulky, non-nucleophilic base, like 2,6-lutidine, to force elimination (E1) rather than substitution. I can re-form the double bond in the new, thermodynamically stable position."
Here are some sample practice problems to get you started:
Number the carbons in both the starting material and the product. Identify exactly which bonds are broken and which new bonds are formed.
Determining conrotatory vs. disrotatory ring closing/opening based on Δ (heat) or 3. Stereoselective Synthesis