This usually means the DLCs were installed before the patch. Re-run the patch or verify file integrity via Steam.
The October 2016 release is distinguished by the inclusion of three pivotal Downloadable Content (DLC) packs that fundamentally altered the gameplay scope. omsi 2 incl all dlc update 03102016
Select the Omsi.exe executable from your 03102016 directory. This usually means the DLCs were installed before the patch