By properly pathing the .IDX / .LIB files, hooking up the mandatory 4.7kΩ I2C pull-up resistors, and linking the internal firmware file, your MAX30100 Proteus simulation will run smoothly without errors.
Download the ZIP file from the link above and extract the contents.
: Look for a dedicated "Pulse Oximeter" or "Heart Beat Sensor" library package. These are often hosted on sites like The Engineering Projects Locate the Proteus Library Folder Right-click your Proteus shortcut and select Open file location