foundational-pillars Foundational Pillars Covered in the Text
| | Specific Additions and Expansions | |---|---| | Molecular Biology Tools | Coverage of the role of small RNAs as regulators, transcription/translation differences between prokaryotes and eukaryotes, and epigenomics. | | Advanced Bioprocessing | Cell-free processes, metabolic engineering, and protein engineering. | | Biofuels & Energy | Expanded coverage of biofuels, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions. | | Synthetic Biology | Entirely new section on the growing role of synthetic biology. | | Kinetics & Balances | Population balances and the Gompertz equation for batch growth and product formation. | | Reactor Technology | New discussion of microreactors for scale-up/scale-down, the development of single-use (disposable) technology in bioprocesses, and rapid scale-up of vaccine production. | | Emerging Technologies | Use of microfabrication, nanobiotechnology, and 3D printing, particularly as related to drug discovery, along with stem cell technology. | | Plant & Animal Biotech | New commercial applications for both animal and plant cell cultures, and key improvements in recombinant DNA microbe engineering. | bioprocess engineering basic concepts 3rd edition pdf
Engineering principles applied to mammalian cell culture for regenerative medicine. | | Synthetic Biology | Entirely new section
representing grams of biomass produced per gram of substrate). 4. Bioreactor Operation and Scalability Translating a reaction from a shake flask to a industrial vessel introduces severe physical constraints. zeta biosystem Cultivation Modes: Closed system where nothing is added or removed. Fed-Batch: | | Emerging Technologies | Use of microfabrication,
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This edition introduces several "hot topics" in modern biotechnology: Synthetic Biology & Genomics: