Protect your red heart containers from taking damage. This ensures your chances for a Devil Deal or Angel Room stay at 100% after a boss fight.

Unlocked by having four or more red heart containers in a single run. She starts with four health containers and the Yum Heart, making her highly forgiving for beginners.

Note: This expansion is for the original Flash-based Binding of Isaac, not the later remake "The Binding of Isaac: Rebirth" (which has its own "Afterbirth" and "Repentance" DLCs).

: If Isaac dies, the player must start from the very beginning, losing all items collected during that run.

Introduces Samson, a high-risk character who gains temporary damage upgrades every time he takes damage during a room clear.

Because The Binding of Isaac does not hold your hand, surviving past the first few floors requires strategy, patience, and a bit of luck. Use these fundamental tips to improve your high score: